There are 346.62 miles from Sioux Falls to Seaton in southeast direction and 471 miles (758.00 kilometers) by car, following the I-29 route.
Sioux Falls and Seaton are 9 hours far apart, if you drive non-stop .
This is the fastest route from Sioux Falls, SD to Seaton, IL. The halfway point is Blairsburg, IA.
Sioux Falls, SD and Seaton, IL are in the same time zone (CDT). Current time in both locations is 12:08 am.
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