There are 290.36 miles from Sioux Falls to Seneca in east direction and 348 miles (560.05 kilometers) by car, following the I-90 route.
Sioux Falls and Seneca are 6 hours 39 mins far apart, if you drive non-stop .
This is the fastest route from Sioux Falls, SD to Seneca, WI. The halfway point is Alden, MN.
Sioux Falls, SD and Seneca, WI are in the same time zone (CDT). Current time in both locations is 1:50 am.
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