Distance between cities › USA › South Dakota › Vermillion, SD › Distance from Vermillion to Adrian Book Hotels

Distance from Vermillion, SD to Adrian, MO

Distance

369 mi

Time

6 hours 49 mins

Gas Cost

$34 - $67

There are 331.55 miles from Vermillion to Adrian in southeast direction and 369 miles (593.85 kilometers) by car, following the I-29 route.

Vermillion and Adrian are 6 hours 49 mins far apart, if you drive non-stop .

This is the fastest route from Vermillion, SD to Adrian, MO. The halfway point is Hamburg, IA.

Vermillion, SD and Adrian, MO are in the same time zone (CDT). Current time in both locations is 12:33 pm.

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Lowest Price Rental Cars in Vermillion, SD

Planning on renting a car to go from Vermillion, SD to Adrian, MO? Here there are some offers to rent a car in Vermillion, SD

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Vermillion »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 14.82 gallons of gas to cover the route between Vermillion, SD and Adrian, MO.

The estimated cost of gas to go from Vermillion to Adrian is $48.34.

During the route, an average car will release 290.36 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Vermillion, SD and Adrian, MO

If you want to meet halfway between Vermillion, SD and Adrian, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 40.598274 and -95.668747, or 40º 35' 53.7864" N, 95º 40' 7.4892" W. This location is 184.51 miles away from Vermillion, SD and Adrian, MO and it would take approximately 3 hours 24 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Hamburg, IA, situated 187 miles from Vermillion, SD and 190 miles from Adrian, MO. It would take 2 hours 56 mins to go from Vermillion to Hamburg and 3 hours 4 mins to go from Adrian to Hamburg.