Distance between cities › USA › South Dakota › Vermillion, SD › Distance from Vermillion to Durham Book Hotels

Distance from Vermillion, SD to Durham, MO

Distance

431 mi

Time

8 hours 33 mins

Gas Cost

$40 - $78

There are 334.41 miles from Vermillion to Durham in southeast direction and 431 miles (693.63 kilometers) by car, following the I-29 route.

Vermillion and Durham are 8 hours 33 mins far apart, if you drive non-stop .

This is the fastest route from Vermillion, SD to Durham, MO.

Vermillion, SD and Durham, MO are in the same time zone (CDT). Current time in both locations is 3:28 pm.

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Lowest Price Rental Cars in Vermillion, SD

Planning on renting a car to go from Vermillion, SD to Durham, MO? Here there are some offers to rent a car in Vermillion, SD

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Vermillion »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 17.30 gallons of gas to cover the route between Vermillion, SD and Durham, MO.

The estimated cost of gas to go from Vermillion to Durham is $56.43.

During the route, an average car will release 338.95 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Vermillion, SD and Durham, MO

If you want to meet halfway between Vermillion, SD and Durham, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 41.533357 and -94.039092, or 41º 32' 0.0852" N, 94º 2' 20.7312" W. This location is 215.39 miles away from Vermillion, SD and Durham, MO and it would take approximately 4 hours 16 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is De Soto, IA, situated 215 miles from Vermillion, SD and 218 miles from Durham, MO. It would take 3 hours 54 mins to go from Vermillion to De Soto and 4 hours 43 mins to go from Durham to De Soto.

Major City Closest to Halfway Point

The major city closest to the halfway point between Vermillion, SD and Durham, MO is Des Moines, IA, situated 236 miles from Vermillion, SD and 193 miles from Durham, MO. It would take 4 hours 18 mins to go from Vermillion to Des Moines and 4 hours 19 mins to go from Durham to Des Moines.