Distance between cities › USA › South Dakota › Vermillion, SD › Distance from Vermillion to Macon Book Hotels

Distance from Vermillion, SD to Macon, MO

Distance

392 mi

Time

7 hours 16 mins

Gas Cost

$37 - $71

There are 312.34 miles from Vermillion to Macon in southeast direction and 392 miles (630.86 kilometers) by car, following the I-29 route.

Vermillion and Macon are 7 hours 16 mins far apart, if you drive non-stop .

This is the fastest route from Vermillion, SD to Macon, MO.

Vermillion, SD and Macon, MO are in the same time zone (CDT). Current time in both locations is 9:05 pm.

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Lowest Price Rental Cars in Vermillion, SD

Planning on renting a car to go from Vermillion, SD to Macon, MO? Here there are some offers to rent a car in Vermillion, SD

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Vermillion »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 15.73 gallons of gas to cover the route between Vermillion, SD and Macon, MO.

The estimated cost of gas to go from Vermillion to Macon is $51.31.

During the route, an average car will release 308.15 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Vermillion, SD and Macon, MO

If you want to meet halfway between Vermillion, SD and Macon, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 40.284961 and -95.479024, or 40º 17' 5.8596" N, 95º 28' 44.4864" W. This location is 195.82 miles away from Vermillion, SD and Macon, MO and it would take approximately 3 hours 38 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Corning, MO, situated 212 miles from Vermillion, SD and 182 miles from Macon, MO. It would take 3 hours 52 mins to go from Vermillion to Corning and 3 hours 29 mins to go from Macon to Corning.