Distance between cities › USA › South Dakota › Vermillion, SD › Distance from Vermillion to Mill Spring Book Hotels

Distance from Vermillion, SD to Mill Spring, MO

Distance

653 mi

Time

12 hours 28 mins

Gas Cost

$61 - $118

There are 515.02 miles from Vermillion to Mill Spring in southeast direction and 653 miles (1,050.90 kilometers) by car, following the I-29 route.

Vermillion and Mill Spring are 12 hours 28 mins far apart, if you drive non-stop .

This is the fastest route from Vermillion, SD to Mill Spring, MO.

Vermillion, SD and Mill Spring, MO are in the same time zone (CDT). Current time in both locations is 4:37 pm.

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Lowest Price Rental Cars in Vermillion, SD

Planning on renting a car to go from Vermillion, SD to Mill Spring, MO? Here there are some offers to rent a car in Vermillion, SD

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Vermillion »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 26.24 gallons of gas to cover the route between Vermillion, SD and Mill Spring, MO.

The estimated cost of gas to go from Vermillion to Mill Spring is $85.58.

During the route, an average car will release 514.03 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Vermillion, SD and Mill Spring, MO

If you want to meet halfway between Vermillion, SD and Mill Spring, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 38.819858 and -94.513017, or 38º 49' 11.4888" N, 94º 30' 46.8612" W. This location is 326.64 miles away from Vermillion, SD and Mill Spring, MO and it would take approximately 6 hours 14 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Belton, MO, situated 336 miles from Vermillion, SD and 319 miles from Mill Spring, MO. It would take 6 hours 14 mins to go from Vermillion to Belton and 6 hours 20 mins to go from Mill Spring to Belton.

Major City Closest to Halfway Point

The major city closest to the halfway point between Vermillion, SD and Mill Spring, MO is Kansas City, MO, situated 314 miles from Vermillion, SD and 339 miles from Mill Spring, MO. It would take 5 hours 44 mins to go from Vermillion to Kansas City and 6 hours 44 mins to go from Mill Spring to Kansas City.