Distance between cities › USA › South Dakota › Vermillion, SD › Distance from Vermillion to Saint Clair Book Hotels

Distance from Vermillion, SD to Saint Clair, MO

Distance

548 mi

Time

10 hours 15 mins

Gas Cost

$51 - $99

There are 437 miles from Vermillion to Saint Clair in southeast direction and 548 miles (881.92 kilometers) by car, following the I-29 route.

Vermillion and Saint Clair are 10 hours 15 mins far apart, if you drive non-stop .

This is the fastest route from Vermillion, SD to Saint Clair, MO.

Vermillion, SD and Saint Clair, MO are in the same time zone (CDT). Current time in both locations is 1:59 pm.

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Lowest Price Rental Cars in Vermillion, SD

Planning on renting a car to go from Vermillion, SD to Saint Clair, MO? Here there are some offers to rent a car in Vermillion, SD

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Vermillion »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 22 gallons of gas to cover the route between Vermillion, SD and Saint Clair, MO.

The estimated cost of gas to go from Vermillion to Saint Clair is $71.76.

During the route, an average car will release 431.01 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Vermillion, SD and Saint Clair, MO

If you want to meet halfway between Vermillion, SD and Saint Clair, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 39.396423 and -94.789667, or 39º 23' 47.1228" N, 94º 47' 22.8012" W. This location is 273.89 miles away from Vermillion, SD and Saint Clair, MO and it would take approximately 5 hours 7 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Platte City, MO, situated 291 miles from Vermillion, SD and 257 miles from Saint Clair, MO. It would take 5 hours 16 mins to go from Vermillion to Platte City and 5 hours 1 min to go from Saint Clair to Platte City.

Major City Closest to Halfway Point

The major city closest to the halfway point between Vermillion, SD and Saint Clair, MO is Kansas City, MO, situated 314 miles from Vermillion, SD and 230 miles from Saint Clair, MO. It would take 5 hours 44 mins to go from Vermillion to Kansas City and 4 hours 31 mins to go from Saint Clair to Kansas City.