Distance between cities › USA › South Dakota › Vermillion, SD › Distance from Vermillion to Seneca Book Hotels

Distance from Vermillion, SD to Seneca, SD

Distance

277 mi

Time

5 hours 35 mins

Gas Cost

$25 - $48

There are 203.42 miles from Vermillion to Seneca in northwest direction and 277 miles (445.79 kilometers) by car, following the US-81 route.

Vermillion and Seneca are 5 hours 35 mins far apart, if you drive non-stop .

This is the fastest route from Vermillion, SD to Seneca, SD. The halfway point is Mount Vernon, SD.

Vermillion, SD and Seneca, SD are in the same time zone (CDT). Current time in both locations is 11:14 am.

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Lowest Price Rental Cars in Vermillion, SD

Planning on renting a car to go from Vermillion, SD to Seneca, SD? Here there are some offers to rent a car in Vermillion, SD

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Vermillion »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 11.12 gallons of gas to cover the route between Vermillion, SD and Seneca, SD.

The estimated cost of gas to go from Vermillion to Seneca is $34.88.

During the route, an average car will release 217.96 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.14 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Vermillion, SD and Seneca, SD

If you want to meet halfway between Vermillion, SD and Seneca, SD or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 43.695026 and -98.297791, or 43º 41' 42.0936" N, 98º 17' 52.0476" W. This location is 138.50 miles away from Vermillion, SD and Seneca, SD and it would take approximately 2 hours 47 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Mount Vernon, SD, situated 144 miles from Vermillion, SD and 155 miles from Seneca, SD. It would take 1 hour 58 mins to go from Vermillion to Mount Vernon and 3 hours 27 mins to go from Seneca to Mount Vernon.