Distance between cities › USA › South Dakota › Vermillion, SD › Distance from Vermillion to Wheaton Book Hotels

Distance from Vermillion, SD to Wheaton, MO

Distance

499 mi

Time

9 hours 27 mins

Gas Cost

$46 - $90

There are 442.75 miles from Vermillion to Wheaton in southeast direction and 499 miles (803.06 kilometers) by car, following the I-29 route.

Vermillion and Wheaton are 9 hours 27 mins far apart, if you drive non-stop .

This is the fastest route from Vermillion, SD to Wheaton, MO. The halfway point is Fillmore, MO.

Vermillion, SD and Wheaton, MO are in the same time zone (CDT). Current time in both locations is 5:55 pm.

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Lowest Price Rental Cars in Vermillion, SD

Planning on renting a car to go from Vermillion, SD to Wheaton, MO? Here there are some offers to rent a car in Vermillion, SD

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Vermillion »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 20.03 gallons of gas to cover the route between Vermillion, SD and Wheaton, MO.

The estimated cost of gas to go from Vermillion to Wheaton is $65.33.

During the route, an average car will release 392.40 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Vermillion, SD and Wheaton, MO

If you want to meet halfway between Vermillion, SD and Wheaton, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 39.985214 and -95.013931, or 39º 59' 6.7704" N, 95º 0' 50.1516" W. This location is 249.36 miles away from Vermillion, SD and Wheaton, MO and it would take approximately 4 hours 43 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Fillmore, MO, situated 249 miles from Vermillion, SD and 259 miles from Wheaton, MO. It would take 3 hours 48 mins to go from Vermillion to Fillmore and 4 hours 22 mins to go from Wheaton to Fillmore.