Distance between cities › USA › South Dakota › Vermillion, SD › Distance from Vermillion to Wheeling Book Hotels

Distance from Vermillion, SD to Wheeling, MO

Distance

342 mi

Time

6 hours 18 mins

Gas Cost

$32 - $62

There are 276.73 miles from Vermillion to Wheeling in southeast direction and 342 miles (550.40 kilometers) by car, following the I-29 route.

Vermillion and Wheeling are 6 hours 18 mins far apart, if you drive non-stop .

This is the fastest route from Vermillion, SD to Wheeling, MO. The halfway point is Hamburg, IA.

Vermillion, SD and Wheeling, MO are in the same time zone (CDT). Current time in both locations is 5:55 pm.

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Lowest Price Rental Cars in Vermillion, SD

Planning on renting a car to go from Vermillion, SD to Wheeling, MO? Here there are some offers to rent a car in Vermillion, SD

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Vermillion »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 13.73 gallons of gas to cover the route between Vermillion, SD and Wheeling, MO.

The estimated cost of gas to go from Vermillion to Wheeling is $44.79.

During the route, an average car will release 269 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Vermillion, SD and Wheeling, MO

If you want to meet halfway between Vermillion, SD and Wheeling, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 40.635498 and -95.711128, or 40º 38' 7.7928" N, 95º 42' 40.0608" W. This location is 170.94 miles away from Vermillion, SD and Wheeling, MO and it would take approximately 3 hours 9 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Hamburg, IA, situated 186 miles from Vermillion, SD and 159 miles from Wheeling, MO. It would take 2 hours 51 mins to go from Vermillion to Hamburg and 2 hours 40 mins to go from Wheeling to Hamburg.