Distance between cities › USA › Missouri › Wappapello, MO › Distance from Wappapello to Waterloo Book Hotels

Distance from Wappapello, MO to Waterloo, SC

Distance

643 mi

Time

12 hours 30 mins

Gas Cost

$60 - $116

There are 494.35 miles from Wappapello to Waterloo in southeast direction and 643 miles (1,034.81 kilometers) by car, following the I-24 route.

Wappapello and Waterloo are 12 hours 30 mins far apart, if you drive non-stop .

This is the fastest route from Wappapello, MO to Waterloo, SC.

Please note the time difference between Wappapello, MO and Waterloo, SC is 1 hour. The current time in Wappapello is 3:56 pm and the current time in Waterloo is 4:56 pm.

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Lowest Price Rental Cars in Wappapello, MO

Planning on renting a car to go from Wappapello, MO to Waterloo, SC? Here there are some offers to rent a car in Wappapello, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Wappapello »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 25.82 gallons of gas to cover the route between Wappapello, MO and Waterloo, SC.

The estimated cost of gas to go from Wappapello to Waterloo is $84.21.

During the route, an average car will release 505.78 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Wappapello, MO and Waterloo, SC

If you want to meet halfway between Wappapello, MO and Waterloo, SC or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 36.125078 and -85.680489, or 36º 7' 30.2808" N, 85º 40' 49.7604" W. This location is 321.40 miles away from Wappapello, MO and Waterloo, SC and it would take approximately 6 hours 15 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Baxter, TN, situated 319 miles from Wappapello, MO and 326 miles from Waterloo, SC. It would take 6 hours 11 mins to go from Wappapello to Baxter and 6 hours 28 mins to go from Waterloo to Baxter.