Distance between cities › USA › Missouri › Wappapello, MO › Distance from Wappapello to Wise Book Hotels

Distance from Wappapello, MO to Wise, NC

Distance

824 mi

Time

15 hours 33 mins

Gas Cost

$77 - $149

There are 670.64 miles from Wappapello to Wise in east direction and 824 miles (1,326.10 kilometers) by car, following the I-81 route.

Wappapello and Wise are 15 hours 33 mins far apart, if you drive non-stop .

This is the fastest route from Wappapello, MO to Wise, NC.

Please note the time difference between Wappapello, MO and Wise, NC is 1 hour. The current time in Wappapello is 10:39 am and the current time in Wise is 11:39 am.

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Lowest Price Rental Cars in Wappapello, MO

Planning on renting a car to go from Wappapello, MO to Wise, NC? Here there are some offers to rent a car in Wappapello, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Wappapello »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 33.08 gallons of gas to cover the route between Wappapello, MO and Wise, NC.

The estimated cost of gas to go from Wappapello to Wise is $107.92.

During the route, an average car will release 648.18 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.26 per gallon of regular gas. Price last updated on March 12, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Wappapello, MO and Wise, NC

If you want to meet halfway between Wappapello, MO and Wise, NC or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 35.894259 and -84.1926, or 35º 53' 39.3324" N, 84º 11' 33.36" W. This location is 411.90 miles away from Wappapello, MO and Wise, NC and it would take approximately 7 hours 46 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Farragut, TN, situated 414 miles from Wappapello, MO and 414 miles from Wise, NC. It would take 7 hours 54 mins to go from Wappapello to Farragut and 7 hours 50 mins to go from Wise to Farragut.

Major City Closest to Halfway Point

The major city closest to the halfway point between Wappapello, MO and Wise, NC is Knoxville, TN, situated 427 miles from Wappapello, MO and 398 miles from Wise, NC. It would take 8 hours 7 mins to go from Wappapello to Knoxville and 7 hours 28 mins to go from Wise to Knoxville.