Distance between cities › USA › Louisiana › Eunice, LA › Distance from Eunice to Cairo Book Hotels

Distance from Eunice, LA to Cairo, MO

Distance

742 mi

Time

14 hours 53 mins

Gas Cost

$70 - $136

There are 623.06 miles from Eunice to Cairo in north direction and 742 miles (1,194.13 kilometers) by car, following the US-165 route.

Eunice and Cairo are 14 hours 53 mins far apart, if you drive non-stop .

This is the fastest route from Eunice, LA to Cairo, MO. The halfway point is Southaven, MS.

Eunice, LA and Cairo, MO are in the same time zone (CDT). Current time in both locations is 2:56 am.

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Lowest Price Rental Cars in Eunice, LA

Planning on renting a car to go from Eunice, LA to Cairo, MO? Here there are some offers to rent a car in Eunice, LA

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Eunice »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 29.81 gallons of gas to cover the route between Eunice, LA and Cairo, MO.

The estimated cost of gas to go from Eunice to Cairo is $98.10.

During the route, an average car will release 583.99 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.29 per gallon of regular gas. Price last updated on March 13, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Eunice, LA and Cairo, MO

If you want to meet halfway between Eunice, LA and Cairo, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 35.053062 and -90.024765, or 35º 3' 11.0232" N, 90º 1' 29.154" W. This location is 371.10 miles away from Eunice, LA and Cairo, MO and it would take approximately 7 hours 26 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest city to the halfway point is Southaven, MS, situated 449 miles from Eunice, LA and 443 miles from Cairo, MO. It would take 6 hours 55 mins to go from Eunice to Southaven and 6 hours 39 mins to go from Cairo to Southaven.

Major City Closest to Halfway Point

The major city closest to the halfway point between Eunice, LA and Cairo, MO is Memphis, TN, situated 461 miles from Eunice, LA and 432 miles from Cairo, MO. It would take 7 hours 10 mins to go from Eunice to and 6 hours 28 mins to go from Cairo to Memphis.