Distance between cities › USA › Ohio › Lisbon, OH › Distance from Lisbon to Cairo Book Hotels

Distance from Lisbon, OH to Cairo, MO

Distance

721 mi

Time

13 hours 52 mins

Gas Cost

$66 - $128

There are 622.15 miles from Lisbon to Cairo in west direction and 721 miles (1,160.34 kilometers) by car, following the I-70 route.

Lisbon and Cairo are 13 hours 52 mins far apart, if you drive non-stop .

This is the fastest route from Lisbon, OH to Cairo, MO.

Please note the time difference between Lisbon, OH and Cairo, MO is 1 hour. The current time in Lisbon is 9:03 pm and the current time in Cairo is 8:03 pm.

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Lowest Price Rental Cars in Lisbon, OH

Planning on renting a car to go from Lisbon, OH to Cairo, MO? Here there are some offers to rent a car in Lisbon, OH

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Lisbon »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 28.95 gallons of gas to cover the route between Lisbon, OH and Cairo, MO.

The estimated cost of gas to go from Lisbon to Cairo is $92.77.

During the route, an average car will release 567.25 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.20 per gallon of regular gas. Price last updated on March 11, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Lisbon, OH and Cairo, MO

If you want to meet halfway between Lisbon, OH and Cairo, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 39.91844 and -86.57659, or 39º 55' 6.384" N, 86º 34' 35.724" W. This location is 360.46 miles away from Lisbon, OH and Cairo, MO and it would take approximately 6 hours 56 mins to reach the halfway point from both locations.

Closest City or Town to Halfway Point

The closest town to the halfway point is Lizton, IN, situated 359 miles from Lisbon, OH and 363 miles from Cairo, MO. It would take 7 hours 12 mins to go from Lisbon to Lizton and 6 hours 43 mins to go from Cairo to Lizton.

Major City Closest to Halfway Point

The major city closest to the halfway point between Lisbon, OH and Cairo, MO is Indianapolis, IN, situated 336 miles from Lisbon, OH and 387 miles from Cairo, MO. It would take 6 hours 43 mins to go from Lisbon to Indianapolis and 7 hours 16 mins to go from Cairo to Indianapolis.