Distance between cities › USA › Missouri › Madison, MO › Distance from Madison to Cairo Book Hotels

Distance from Madison, MO to Cairo, MO

Distance

17 mi

Time

24 minutes

Gas Cost

$1 - $3

There are 12.58 miles from Madison to Cairo in northwest direction and 17 miles (27.36 kilometers) by car, following the US-24 and MO 151 route.

Madison and Cairo are 24 minutes far apart, if you drive non-stop .

This is the fastest route from Madison, MO to Cairo, MO.

Madison, MO and Cairo, MO are in the same time zone (CDT). Current time in both locations is 12:46 am.

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Lowest Price Rental Cars in Madison, MO

Planning on renting a car to go from Madison, MO to Cairo, MO? Here there are some offers to rent a car in Madison, MO

Small

From $14

Intermediate

From $18

Full-size

From $24

SUVs

From $28

Vans

From $40

Compare rental car prices in Madison »

Gas Consumption and Emissions

A car with a fuel efficiency of MPG will need 0.69 gallons of gas to cover the route between Madison, MO and Cairo, MO.

The estimated cost of gas to go from Madison to Cairo is $2.08.

During the route, an average car will release 13.48 pounds of CO₂ to the atmosphere. The carbon footprint would be 0.79 pounds of CO₂ per mile.

Average USA gas price used for calculation is $3.03 per gallon of regular gas. Price last updated on March 11, 2026.
Read more about our CO₂ calculation.

Halfway Point Between Madison, MO and Cairo, MO

If you want to meet halfway between Madison, MO and Cairo, MO or just make a stop in the middle of your trip, the exact coordinates of the halfway point of this route are 39.462379 and -92.355476, or 39º 27' 44.5644" N, 92º 21' 19.7136" W. This location is 8.56 miles away from Madison, MO and Cairo, MO and it would take approximately 12 minutes to reach the halfway point from both locations.